we are hearing about a new covid varient that has poppe dup that the previous vaccines won't stop and President Biden announces he will have a new vaccine and you will take it and like it.
Or maybe not. The government here can't give away the previous bivalent vaccine (I have even seen ads on youtube pushing it).
And we are also supposed to get influenza and the new RSV vaccines.
Well, those illnesses are nasty but those vaccines are unproven: Give monoclonal antibodies to babies, or vaccinate their moms when pregnant? I will have to look into this. RSV in babies is nasty and can kill and some develop repeated chest infections as toddlers and live in your office with repeated infections, but a previous vaccine caused lymphatic hypertrophy in the intestines that caused intrasusseption and killed kids so was taken off the market. So I will have to look into this.
But although lots of hype about the newest covid varient, there isn't much hard data out there about if it is fatal like the original covid or just a bad cold like Omicron.
And yes I know they are saying the percentage more of illness out there, but without numbers and when a lot of folks are no longr testing, you don't know what this means.
August 9 (GMT) Updates 132 new cases and 3 new deaths in the Philippines
so no big surge in deaths.
Dr. C. discusses.
the problem? The observation that vaccine makes you more prone to get another infection. Dr. C also has taught physiology so here he explains why this is happening.
the comments on the video:
BA.2.86 may be more capable of causing infection in people who have previously had COVID-19 or who have received COVID-19 vaccines. ? stimulation of T suppressor (regulatory) cells ? stimulation of IgG4 https://www.science.org/doi/10.1126/s... No evidence BA.2.86 causing more severe illness. Updated vaccines will be available as early as mid-September What can you do to protect yourself and others as we learn more? Get your COVID-19 vaccines, as recommended''CDC Report COVID-19 Vaccines Are Safe, Effective, and Free Everyone 6 months and older should get an updated COVID-19 vaccine. BA.2.86 https://www.nature.com/articles/d4158... Many spike protein changes (explain vaccine immune escape) Could out compete common EG.5 (Latest COVID-19 booster vaccines are based on XBB.1.5) Jesse Bloom, viral evolutionary biologist, Fred Hutchinson Cancer Center Seattle, Washington “I don’t think anybody needs to be alarmed by this,” “The most likely scenario is that this variant fizzles out, and in a month nobody other than people like me even remember that it existed.” Even if BA.2.86 does becomes widespread, and proves adept at dodging neutralizing antibodies,
I got the AZ vaccine, which gives blood clots especially in the young, and he notes it doesn't seem to be affecting the immune system this way. So I am safe, sort of.
The Science article discusses the immune part:
In a recent paper published in Science Immunology, Irrgang et al. (1) showed that administering three doses of an mRNA vaccine encoding the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike antigen eventually results in an increased proportion of antigen-specific antibodies of the immunoglobulin G4 (IgG4) subtype, but IgG4 antibodies were not induced after an adenoviral vector vaccine. Similar results were observed in a separate, contemporaneous study (2). These results provoke a reconsideration of some fundamental immune mechanisms unique to the human immune system but also raise issues that may (or may not) have practical relevance in terms of vaccinology and public health.
...We now know that structural differences in a loop in the CH2 (second constant heavy chain) domain of IgG4 (when compared with IgG1) impair its binding to C1q and to most activating Fc receptors. This has led to the view that IgG4 may have evolved to dampen inflammation and functions essentially as an antigen sink.,,,
fab arm exchange is discussed here;
the title of the paper:Is it bad, is it good, or is IgG4 just misunderstood?
I downloaded a bunch of stuff about immunology which wasn't around when I studied in medical school 50 years ago, so watch Dr. C for details
but the important question is not answered in detail: apparently the summary is:
No evidence BA.2.86 causing more severe illness.
since a bad ordinary chest cold could kill me, that could be a problem.
So now answer this question: Will Ivermectin treat or prevent that new varient? Anyone? Anyone?
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