Elephantiasis is a disease where the filaria worm blocks the lymph node and you end up with a huge leg (and/or scrotum). WIKIPEDIA ARTICLE.
This Science daily article discusses how Cameroon is trying to control this disabling disease: by giving a yearly dose of the anti parasite drug.
the infection rate is now so low that the country is considering stopping the program.
another mosquito based disease.
we used to see people with itchy nodules and would biopsy the nodules to check for this, although there is also a blood test.
I can't remember the name of the medicine used to treat the disease back then, but this article discusses the present day treatment.
You can also kill the parasite by using tetracycline, which kills a bacteria that the worm needs to live.
however, surgery is required for the damage.