Friday, December 15, 2017

Generics from Canada

I am old enough to remember when importing cheap generic drugs from Canada into the US was a big political controversy.

I am posting the stories below just for my own information, in case there is a conspiracy behind these deaths:



Read this story in the UK telegraph: Canadian pharmaceutical founder and wife dead in suspicious circumstances.

This old 2010 story at the NYTimes notes that their generic medicines have problems with quality control. One of their products is a fentanyl patch without gel: presumably not as easy to abuse.

and a 2014 story says they were suing Canada for not letting them import their drugs that were made in India.

and this older article notes they were helping supply cheap HIV medicines to Africa but found the red tape was so expensive they didn't plan to continue. More here about the problem of intellectual property and trade rights in the Canadian generic drug companies trying to supply medicines to third world charities.

or is it because they are in trouble for stealing trade secrets from another drug company? Philly.com has the story of the big lawsuit over this.

WtF: Information on smoking a non-gel Fentanyl patches?... I was aware of the abuse but not that the powers that be allowed addicts place these discussions on the internet.

medical article on the problem.

so for conspiracy folks, we have sex, drugs and, well maybe not rock and roll but business shennanigans.

And of course, mentioning HIV drugs to Africa being in the conspiracy of Arkancide.

Yes, I am being sarcastic.

substandard, contaminated, and even counterfeit drugs are a big problem here, so I will keep an eye on it.

Monday, December 11, 2017

Baby Body parts

But one of the more serious undercover journalism by non professionals was the publicity about the lucrative market of selling baby parts from abortions: Something that is illegal.

Didn't get much publicity, of course.

and no one in the Obama administration justice Dept gave it glance (although the FBI might now look into it ).

But I did run across this article: The company making huge profits on the illegal scam got shut down by... the local Orange County district attorney in California!?

LATimes: 2 companies reahch $7.7 million dollar settlement

translation: they got shut down, and a small fine. Where did that 7 million dollar figure come from? That's what their illegal inventory of baby body parts was worth, and now they will have to give them away for "research".

Wesley Smith points out that the deal is not perfect, but they did get shut down... and no punishment for planned parenthood who were the source of the body parts...

and of course, PP and others made a lot of money out of this: did this bias their counseling sessions for the mothers, to push abortion but no other options (something unethical in medicine)...

and of course, one doubts that any of the moms were aware that the type of abortion done (so that the body parts were easier to "harvest") was more dangerous to her health too... nor were the mothers compensated, of course (which would be a bigger ethical problems: carrying the kid to make money then killing him).

Mr Burke, call your office. Mr Hare please answer your page...Dr. Knox is on line.

Friday, December 8, 2017

Junk food diarrhea

from StrategyPage:

 switching from one's normal Asian diet to a rich western diet causes diarrhea, and this could kill a lot of malnourished North Koreans if that country gets taken over by the South or by China.


Now doctors realized that given the state of North Korean soldiers’ digestive tract because of the bad food and water, suddenly switching to South Korean snack foods and other delicacies the northerners had never had would induce diarrhea and disability until their digestive tract could adjust to the Western diet.
This problem was not unknown in South Korea. That’s because of the more than 500,000 South Korean troops who have served, individually, in U.S. Army units since 1950. ...
The KATUSAs are treated just like the American troops, living in the same barracks, eating in the same mess halls and getting the same medical care.
A common medical problem with KATUSAs was diarrhea because the KATUSA did not follow instructions and shift gradually to the very different (especially in terms of sweets, processed foods and so on) food served in the American dining halls and when troops were out in the field. The diarrhea problem was largely gone by the 1980s as the South Korean economy became affluent enough to produce local versions of the American processed and snack foods.

Personally, some of this might be because a lot of American food has ilk in it, and Asians tend to be unable to digest lactose in milk.

but you have to watch when you refeed someone who has been chronically starved or malnourished because they cannot absorb the food.

LINK Some concentration camp survivors died when fed
As did the survivors of Napoleon's Russian debacle.

My main experience is with children suffering from marasmus and kwashiorkor.

The intestinal lining gets thinner and fewer villae to absorb food, so they can't digest stuff.
And often they would just die a week or two later, probably because of nutritional cardiomyopathy. (heart muscle replaced with connective tissue, and too weak to keep beating when the person starts recovering).

Sigh

Thursday, December 7, 2017

the white death: Betty Mac Donald's book

Betty MacDonald is best known for the book and movie: The Egg and I

But she suffered from TB, and also wrote a book The Plague and I.

part of it is here

Friday, December 1, 2017

DENGUE VACCINE SCANDAL

one of the problems with Dengue is that, unlike most diseases that give you immunity, if you get dengue a second time,, you can get a lot sicker: you are more likely to get the hemorrhagic form of the disease if you get a different strain of the disease.

here, Dengue kills a lot of folks and makes more sick.

So they had started using a vaccine in certain areas here: Then the drug company said: there might be side effects

NYTimes article:


The company said further clinical studies had revealed that, in those who had previously had dengue, the vaccine could prevent repeat infection. But for those who had not had dengue, and were vaccinated and later became infected, “more cases of severe disease could occur,” Sanofi said in the advisory... more than 740,000 elementary school students in the Philippines having already received Dengvaxia vaccinations, the government decided to halt the program for the time being..

the gov't defended it's use, noting the World Health Organization okayed it's use.

the Phil Inquirer has more and goes into the worries, but notes that no deaths here so far.

I laugh at the note docs need to take a history if the kids had had the disease: mild cases would never see a doc or be diagnosed since it looks like the flu or other virual illnesses.

but ddeep in the article you note this:
Health advocates are pressing the DOH to file plunder charges against those who implemented the vaccination program.
Duque refused to comment without a review of all the documents and contracts and the circumstances surrounding the immunization program.
The massive program was launched under Health Secretary Janette Garin despite staunch opposition from several medical experts who said the DOH should wait until the study on the vaccine was completed and had enough safeguards for those who would receive it.

Read more: http://newsinfo.inquirer.net/949224/philippine-news-updates-dengue-vaccines-department-of-health-dengue-immunization-program-dengvaxia-2#ixzz503XfG2qJ Follow us: @inquirerdotnet on Twitter | inquirerdotnet on Facebook

Friday, November 24, 2017

Polio update

Doctors are hoping to eradicate polio the way they eliminated smallpox.

CDC report on the program.
CDC notes the support services for the locals are the unsung heroes.

 With more than 300 personnel at national, state, and local government area levels supporting the program’s projects across the states and local government areas, the National Stop Transmission of Polio (NSTOP) programs train health care professionals, native to and living in their respective countries, in polio eradication and field epidemiology. Modeled after the CDC-World Health Organization (WHO) STOP program, the programs receive financial support from the CDC and other international agencies, while receiving technical assistance from CDC’s Global Immunization Division and Field Epidemiology and Laboratory Training Programs (FELTPs).

their reports are quite technical. But for a holistic report on the problem:
StrategyPage has this snip about the problems of doing this in war torn areas.

In northwest Pakistan police arrested five members of the Pakistani Taliban as a result of tips from local residents. Under questioning one of the five admitted who they were and what they were up to..... The five were planning attacks on the polio vaccination effort and any other government operation they could get to.
Vaccination teams are particularly vulnerable because they must visit the most remote and lawless areas to deliver the vaccination to vulnerable children. Parents tend to favor the vaccination and given the proliferation of cell phone service it is rather easy to call in or text a tip about some threat to the vaccination effort.
The Afghan Taliban appear to have realized this but some of their Pakistani counterparts have not or just don’t care. Because of this the Pakistani Taliban have become the major obstacle to finally wiping out polio.
In the last decade the main obstacle has been Islamic terror groups who ban polio vaccinations and attack anyone trying to deliver the vaccine to vulnerable children. Islamic terrorists in general tend to believe the vaccination teams are spying for the government and that the vaccinations are a plot to sterilize Moslems.
In Pakistan and Afghanistan there are still religious problems with vaccination. The Afghan Taliban now openly support the vaccination program but there still some rural areas where local Moslem clerics or teachers continue to denounce the vaccinations. There is a similar situation in Pakistan, where some fringe Islamic groups still try and kill members of the vaccination teams.
Despite the death threats there is another major effort this year to vaccinate vulnerable Afghan and Pakistani children against polio. In 2016 there were 20 cases of polio in Pakistan and 13 in Afghanistan. There were four in Nigeria, a country that is expected to be free of polio this year or next. Despite this continued resistance polio cases in Afghanistan and Pakistan continues to decline. For Afghanistan there have been at least six cases so far in 2017 compared to 13 for 2016. In Pakistan the situation is similar with about the same number of cases in 2017. Nevertheless the global vaccination effort has worked. In the 1980s, when the polio elimination effort began there were 350,000 cases in 125 countries.
For the last several years there have been fewer than a hundred cases worldwide. After a few years of no reported cases polio will gone, as happened with smallpox in the 1970s.


Wednesday, November 22, 2017

Hepatitis: now in LaLaLand

Yes, the lovely city of Los Angeles now has a problem with hepatitis.



 Back In 2012, the Los Angeles Community Action Network predicted that Skid Row was ripe for disease in a report similar to the one earlier this year. Then, just as now, restrooms often lacked soap, water, toilet paper and trash cans.
“The City of Los Angeles has failed miserably when it comes to providing accessible and clean public restrooms, thereby creating and maintaining the human rights violations cited in this report and others,” the report said. “It is an obvious fact that human beings simply must relieve themselves regularly. All residents face the need for public restrooms, it’s just that homeless residents are entirely reliant on public options.”
Maybe they should hire Claire Frazer to tell them how to fight the epidemic




basic hygiene:

Toilets

and hand washing