They have identified a way to enhance regrowth of human corneal tissue to restore vision, using a molecule known as ABCB5, which acts as a marker for hard-to-find limbal stem cells. The research, published in the journal Nature, is also one of the first known examples of constructing a tissue from an adult-derived human stem cell. Limbal stem cells are found in the eye’s basal limbal epithelium, or limbus, and help maintain and regenerate corneal tissue.
related item: Printing new organs.
HOW THEY DID IT
Using a high-tech 'bio-printer', the researchers fabricated a multitude of interconnected tiny fibres to serve as the mold for the artificial blood vessels.
They then covered the 3D printed structure with a cell-rich protein-based material, which was solidified by applying light to it.
Lastly they removed the bio-printed fibres to leave behind a network of tiny channels coated with human endothelial cells, which self organised to form stable blood capillaries in less than a week.
The study reveals that the bioprinted vascular networks promoted significantly better cell survival, differentiation and proliferation compared to cells that received no nutrient supply.
Read more: http://www.dailymail.co.uk/sciencetech/article-2678614/The-end-transplant-waiting-lists-Researchers-reveal-giant-leap-printing-replacement-organs-say-soon-created-demand.html#ixzz36SUrSzdz
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