medical headlines and memories of the good old days of medicine
Monday, October 31, 2022
The explanation of scientific reasons that maybe it was a lab leak
SARS epidemic
At least five independent spill overs of the SARS virus into humans
Live animal markets followed by human to human
E.g. Guangdong Province, November 2002 to January 2003
SARS, later on in 2003 – 2004
Additional independent subsequent spill over infections in humans
Civets identified within 6 months
Early SARS viral samples from humans contained genetic mutations that reflected prior circulation and adaptation in palm civets
In total contrast
Chinese government, asserted that the COVID-19 originated from a natural zoonotic transmission occurring at the Huanan market
Geo-temporal spread of COVID-19 in China, December 31, 2019 to February 11, 2020
Earliest identified SARS-CoV-2 well-adapted for human-to-human transmission
Early SARS-CoV-2 variants had little genetic diversity, 2 nucleotides out of 29,900
(Adenine, Cytosine, Guanine, Uracil)
No evidence of previous intermediate host circulation
Genetic similarity between the environmental samples and human viral samples,
supports the likelihood that the virus found at the Huanan Seafood Market was shed by humans
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